CHEMOENZYMATIC SYNTHESIS AND STEREOCHEMISTRY OF ALEPPOTRIOLOSIDE, A NATURALLY-OCCURRING GLUCOSIDE

被引：17

作者：

TRINCONE, A ^{[1
]}

PAGNOTTA, E ^{[1
]}

SODANO, G ^{[1
]}

机构：

[1] UNIV SALERNO,DIPARTIMENTO FIS,I-84081 BARONISSI,ITALY

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 09期

关键词：

D O I：

10.1016/S0040-4039(00)76233-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The stereochemistry of aleppotrioloside, a naturally occurring glucoside, has been determined as (3S)-3-[(1S)-1-hydroxyethyl]-4-methyl-1,4-pentanediol-1-O-beta-D-glucopyranoside by its synthesis based on two key enzymatic reactions: Pseudomonas fluorescens lipase (PFL) catalyzed enantioselective resolution of an aglycone precursor and transglucosylation of the aglycone by thermophilic beta-glycosidase from Sulfolobus solfataricus.

引用

页码：1415 / 1416

页数：2

共 8 条

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