RELATIONSHIP OF GENERALIZED ANXIETY SYMPTOMS TO URINARY 5-HYDROXYINDOLEACETIC ACID AND VANILLYLMANDELIC ACID

被引:17
作者
GARVEY, MJ [1 ]
NOYES, R [1 ]
WOODMAN, C [1 ]
LAUKES, C [1 ]
机构
[1] UNIV IOWA,COLL MED,DEPT PSYCHIAT,IOWA CITY,IA 52242
关键词
SEROTONIN; NOREPINEPHRINE; HAMILTON RATING SCALE FOR ANXIETY;
D O I
10.1016/0165-1781(94)02510-P
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Urinary levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) and the norepinephrine metabolite vanillylmandelic acid (VMA) were measured in 45 patients with generalized anxiety disorder. Multiple regression analysis demonstrated that the severity of several anxiety symptoms was predicted by levels of 5-HIAA and VMA. These data are consistent with the proposal that serotonin and norepinephrine may be involved in the pathophysiology of anxiety.
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页码:1 / 5
页数:5
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