CLINICAL PRESENTATION OF SUSPECTED MALIGNANT HYPERTHERMIA DURING ANESTHESIA IN 402-PROBANDS

被引:34
作者
ELLIS, FR
HALSALL, PJ
CHRISTIAN, AS
机构
[1] Leeds MH Investigation Unit, University Department of Anaesthesia, St. James's University Hospital, Leeds
[2] Leeds MH Investigation Unit, University Department of Anaesthesia, St. James's University Hospital, Leeds
[3] Leeds Mh Investigation Unit, University Department of Anaesthesia, St. James's University Hospital, Leeds
关键词
Hyperthermia; malignant;
D O I
10.1111/j.1365-2044.1990.tb14566.x
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
As anaesthetists have become more aware of malignant hyperthermia the mortality rate has fallen, but concommitantly the number of dubious and aborted cases has increased. All probands who developed a suspected malignant hyperthermia reaction during anaesthesia and subsequently underwent muscle biopsy were classified according to the clinical presentation. A probability for malignant hyperthermia can be calculated, using the classification, for each type of clinical presentation; this varied from 0.96 to 0.07. Certain clinical features were found to be of more value as predictors than others; these included a high creatine kinase and myoglobinuria. The accuracy of prediction depends on a clear contemporaneous description of the clinical events. Copyright © 1990, Wiley Blackwell. All rights reserved
引用
收藏
页码:838 / 841
页数:4
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