BOTULINUM TOXIN TREATMENT IN PATIENTS WITH FOCAL DYSTONIA AND HEMIFACIAL SPASM - A MULTICENTER STUDY OF THE ITALIAN-MOVEMENT-DISORDER-GROUP

被引：26

作者：

BERARDELLI, A

FORMICA, A

MERCURI, B

ABBRUZZESE, G

AGNOLI, A

AGOSTINO, R

CARACENI, T

CARELLA, F

DEFAZIO, G

DEGRANDIS, D

ELEOPRA, R

GIRLANDA, P

LEPORE, V

MESSINA, C

MILONE, S

PRIORI, A

STOCCHI, F

TUGNOLI, V

MANFREDI, M

机构：

[1] UNIV BARI,MALATTIE NERVOSA & MENTALI CLIN,I-70124 BARI,ITALY

[2] ARCISPEDALE ST ANNA,NEUROL CLIN,FERRARA,ITALY

[3] UNIV GENOA,COLL NEUROL,I-16126 GENOA,ITALY

[4] UNIV MESSINA,NEUROL CLIN,I-98100 MESSINA,ITALY

[5] IST NEUROCHIRURG C BESTA,I-20133 MILAN,ITALY

来源：

ITALIAN JOURNAL OF NEUROLOGICAL SCIENCES | 1993年 / 14卷 / 05期

关键词：

BOTULINUM TOXIN; DYSTONIA; HEMIFACIAL SPASM;

D O I：

10.1007/BF02340723

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In six Centers belonging to the Italian Movement Disorder Study Group, the efficacy of botulinum toxin treatment was evaluated in an open collaborative study in 251 patients with focal dystonia and hemifacial spasm. The percentage of functional improvement ranged from 66% to 81% in patients with blepharospasm, from 40% to 51% in patients with spasmodic torticollis and from 73% to 81% in those with hemifacial spasm. Good results were also obtained in patients with oromandibular dystonia, laryngeal dystonia and writer's cramp. Side effects were mild and transient. Local botulinum toxin injection is the first choice symptomatic treatment in focal dystonia and hemifacial spasm.

引用

页码：361 / 367

页数：7

共 24 条

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