BETA-CORE CHEMICAL AND CLINICAL PROPERTIES

被引：6

作者：

BLITHE, DL

WEHMANN, RE

NISULA, BC

机构：

[1] VET ADM MED CTR,BROOKLYN,NY 11209

[2] SUNY HLTH SCI CTR,BROOKLYN,NY 11209

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1990年 / 1卷 / 08期

关键词：

D O I：

10.1016/1043-2760(90)90098-N

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

β-Core is the most abundant hCG-related molecule in pregnancy urine. The structure of β-core as well as aspects of its metabolic clearance suggest that β-core is a metabolic fragment of the hCG-β subunit. The occurrence of β-core in the urine of patients with a broad spectrum of malignancies imparts an important role to β-core as a tumor marker. The recent development of antisera with enhanced specificity and sensitivity for β-core will facilitate further studies on the clinical significance of this molecule. © 1990.

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页码：394 / 398

页数：5

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