ASYMMETRIC DECARBOXYLATION OF DISUBSTITUTED MALONIC-ACID BY ALCALIGENES-BRONCHISEPTICUS KU 1201

被引：34

作者：

MIYAMOTO, K ^{[1
]}

OHTA, H ^{[1
]}

机构：

[1] KEIO UNIV, FAC SCI & TECHNOL, DEPT CHEM, KOHOKU KU, YOKOHAMA, KANAGAWA 223, JAPAN

来源：

BIOCATALYSIS | 1991年 / 5卷 / 01期

关键词：

ALPHA-ARYLPROPIONIC ACID; ASYMMETRIC DECARBOXYLATION; DISUBSTITUTED MALONIC ACID; ALCALIGENES-BRONCHISEPTICUS;

D O I：

10.3109/10242429109014854

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Optically active αarylpropionic acids constitute a group which involves many useful compounds. We selected a microorganism which has the ability to realize the asymmetric decarboxylation of αmethyl-αphenylmalonic acid to afford optically active αphenylpropionic acid and it identified as Alcaligenes bronchisepticus KU 1201. When the aryl group was phenyl, 4-chlorophenyl, 6-methoxy-2-naphthyl or 2-thienyl, the substrate afforded optically active αarylpropionic acid in high optical and chemical yield. © 1991 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：49 / 60

页数：12

共 12 条

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