CELL DEATH DURING EARLY MORPHOGENESIS - PARALLELS BETWEEN INSECT LIMB AND VERTEBRATE LIMB DEVELOPMENT

被引:39
作者
WHITTEN, JM
机构
[1] Department of Biological Sciences, Northwestern University, Evanston
关键词
D O I
10.1126/science.163.3874.1456
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The complex jointed leg of the adult fly is derived, in the pupal stage, from a simple lobed sac of cells. The gross morphological changes that result in adult shape are effected by a combination of differential cell growth and the programmed death of a large number of imaginal disc cells. Events are closely similar to those occurring in digit formation and limb contouring during vertebrate morphogenesis. In both cases phagocytic blood cells are intimately involved.
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页码:1456 / &
相关论文
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