CEREBRAL CORTICAL MICRO-FLUOROMETRY AT ISOSBESTIC WAVELENGTHS FOR CORRECTION OF VASCULAR ARTIFACT

被引：47

作者：

KRAMER, RS

PEARLSTEIN, RD

机构：

[1] Spetnagel Laboratory for Cerebral Research, Department of Surgery, Duke University Medical Center, Durham

来源：

SCIENCE | 1979年 / 205卷 / 4407期

关键词：

D O I：

10.1126/science.223243

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Microfluorometric measurements of cerebral cortical mitochondrial respiration in vivo are obscured by hemodynamic and oximetric artifacts. Isosbestic fluorometry provides appropriate correction for these vascular phenomena and permits simultaneous evaluation of mitochondrial nicotinamide adenine dinucleotide redox state, microcirculatory volume, and hemoglobin oxygenation.

引用

页码：693 / 696

页数：4

共 23 条

[1] INSTRUMENTATION FOR INVIVO CEREBRAL NADH STUDIES IN SQUIRREL-MONKEY [J].