A NEW SURFACTANT SERIES, THE N-ALKYLAMINO-1-DEOXYLACTITOLS - APPLICATION FOR EXTRACTION OF OP OPIATE RECEPTORS FROM FROG BRAIN

被引：30

作者：

GARELLICALVET, R

LATGE, P

RICO, I

LATTES, A

PUGET, A

机构：

[1] UNIV TOULOUSE 3,IMRCP LAB,CNRS,UA 470,118 ROUTE NARBONNE,F-31062 TOULOUSE,FRANCE

[2] LAB PHARMACOL & TOXICOL FONDAMENTALES,CNRS,UPR 8221,TOULOUSE,FRANCE

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1992年 / 1109卷 / 01期

关键词：

OPIATE RECEPTOR; SURFACTANT; (FROG BRAIN);

D O I：

10.1016/0005-2736(92)90186-P

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new series of surfactants, the N-alkylamino-l-deoxylactitols, was prepared and employed to extract 'op' opiate receptors from frog brain. These surfactants are both cheap and convenient to prepare. Receptors were reproducibly extracted in a good yield using N-nonylamino-1-deoxylactitol. This derivative, which was not denaturing during the extraction process, could thus be used instead of the more costly digitonin, whose rather variable purity affects yield.

引用

页码：55 / 58

页数：4

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