STEREOSELECTIVE SYNTHESIS OF (E)-GAMMA,DELTA-UNSATURATED, AND (Z)GAMMA,DELTA-UNSATURATED KETONES USING TRANS-2-PHENYLTHIOCYCLOBUTYL KETONES

被引：10

作者：

FUJIWARA, T ^{[1
]}

IWASAKI, T ^{[1
]}

TAKEDA, T ^{[1
]}

机构：

[1] TOKYO UNIV AGR & TECHNOL, DEPT APPL CHEM, KOGANEI, TOKYO 184, JAPAN

来源：

CHEMISTRY LETTERS | 1993年 / 08期

关键词：

D O I：

10.1246/cl.1993.1321

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of 1-methoxymethyl-2-phenylthiocyclobutanes with phenylthiotrimethylsilane followed by hydrolysis gave (E)- and (Z)-gamma,delta -unsaturated ketones with high stereoselectivity. The starting materials were easily prepared by die stereoselective addition of Grignard reagents to trans -2-phenylthiocyclobutyl ketones.

引用

页码：1321 / 1324

页数：4

共 7 条

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