EFFECTS OF THYROTROPIN RELEASING HORMONE (TRH) ON THE GASTRO-INTESTINAL TRACT

被引：54

作者：

MORLEY, JE

STEINBACH, JH

FELDMAN, EJ

SOLOMON, TE

机构：

[1] VET ADM WADSWORTH HOSP CTR,CTR ULCER RES & EDUC,LOS ANGELES,CA 90073

[2] UNIV CALIF LOS ANGELES,DEPT MED,LOS ANGELES,CA 90024

来源：

LIFE SCIENCES | 1979年 / 24卷 / 12期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0024-3205(79)90038-9

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Thyrotropin-releasing hormone (TRH) immunoreactivity is distributed throughout the gastrointestinal tract and the pancreas. We have studied the effect of TRH on several gastrointestinal functions in intact, unanesthetized dogs. Intravenous TRH stimulated gastric action potentials (p<0.01) and transiently inhibited tetragastrin-stimulated gastric acid secretion (p<0.05). TRH had no effect on basal or secretin-stimulated pancreatic exocrine secretion. TRH did not alter water absorption in dogs with Thiry-Vella loops constructed from proximal jejunum. © 1979.

引用

页码：1059 / 1065

页数：7

共 14 条

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