THE EFFECT OF WOOD-DERIVED INHIBITORS ON 2,3-BUTANEDIOL PRODUCTION BY KLEBSIELLA-PNEUMONIAE

被引:23
作者
NISHIKAWA, NK
SUTCLIFFE, R
SADDLER, JN
机构
[1] Forintek Canada Corp, Ottawa, Can, Forintek Canada Corp, Ottawa, Can
关键词
ALCOHOLS - Production - BIOTECHNOLOGY - CELL CULTURE - Batch - SOLVENTS - Production;
D O I
10.1002/bit.260310617
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Four potential inhibitors, hydroxymethylfurfural, furfural syringaldehyde and vanillin, were assayed over a range of concentrations and times to simulate the amounts that might be expected to accumulate when the hydrolyzed water-soluble fraction from steam-treated aspenwood was added in a fed-batch mode to K. pneumoniae. Combinations of the individual materials resulted in a cumulative inhibitory effect. Prolonged incubation could alleviate some of the inhibition.
引用
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页码:624 / 627
页数:4
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