ELEVATION OF FACILITATED GLUCOSE-TRANSPORTER MESSENGER-RNA IN HUMAN HEPATOCELLULAR-CARCINOMA

被引：51

作者：

SU, TS

TSAI, TF

CHI, CW

HAN, SH

CHOU, CK

机构：

[1] NATL YANG MING MED COLL,GRAD INST MICROBIOL & IMMUNOL,TAIPEI 11217,TAIWAN

[2] NATL YANG MING MED COLL,GRAD INST GENET,TAIPEI 11217,TAIWAN

来源：

HEPATOLOGY | 1990年 / 11卷 / 01期

关键词：

D O I：

10.1002/hep.1840110120

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Complementary DNA of a rat brain glucose transporter gene was used to examine the expression of glucose‐transporter messenger RNA in paired human hepatocellular carcinomas and adjacent nontumorous liver tissues, as well as in human hepatoma cell lines and human fetal liver samples. High expression of a major 2.8‐kilobase glucose‐transporter transcript was seen in all hepatoma cell lines and fetal liver samples examined, whereas a much lower level of expression was observed in liver tissues. When pairs of liver tissues were examined, elevation of glucose‐transporter RNA levels was observed in most of the hepatocellular carcinoma tissues examined. Copyright © 1990 American Association for the Study of Liver Diseases

引用

页码：118 / 122

页数：5

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