GAMMA-DELTA T-CELL RECEPTOR POSITIVE T-CELL CLONES DERIVED FROM HUMAN HEART-TRANSPLANTS DO NOT SHOW DONOR-SPECIFIC CYTOTOXICITY

γδ T-cell receptor-positive T-cell clones were obtained from three endomyocardial biopsies taken from two patients. Clones obtained from two biopsies from patient A, one taken during rejection and one after resolution of this rejection, were WT31-, 11F2+, TiγA-, δTcS1+. Clones from patient B grown from a biopsy without histologic signs of rejection were either WT31-, 11F2+, TiγA+, δTcS1-, or WT31+. All γδ T-cell receptor-positive clones had cytolytic potential but did not demonstrate donor-specific lysis. © 1990.