TOTAL SYNTHESES OF BOTH ENANTIOMERS OF SARCOPHYTOL-A AND SARCOPHYTOL-T BASED ON STEREOSPECIFIC [2,3]WITTIG REARRANGEMENT

被引：17

作者：

KODAMA, M

YOSHIO, S

YAMAGUCHI, S

FUKUYAMA, Y

TAKAYANAGI, H

MORINAKA, Y

USUI, S

FUKAZAWA, Y

机构：

[1] MITSUBISHI KASEI CORP,RES CTR,PHARMACEUT LAB,MIDORI KU,YOKOHAMA,KANAGAWA 227,JAPAN

[2] HIROSHIMA UNIV,DEPT CHEM,HIGASHIHIROSHIMA 724,JAPAN

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 52期

关键词：

D O I：

10.1016/S0040-4039(00)61357-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Both enantiomers of sarcophytols A (1) and T (2), cembranolide diterpenes isolated from a soft coral, were synthesized from a common chiral intermediate, obtained by baker's yeast reduction, using a stereospecific [2,3]Wittig rearrangement as the key step.

引用

页码：8453 / 8456

页数：4

共 17 条

[1]

FUJIKI H, 1989, J CANCER RES CLIN, V31, P3317

[2] CONFORMATIONAL STUDY OF THE CEMBRANOLIDE DITERPENE DENTICULATOLIDE BY MOLECULAR MECHANICS METHOD [J].