MOLECULAR CHARACTERIZATION AND ANTIBIOTIC SUSCEPTIBILITY OF VIBRIO-CHOLERAE NON-O1

被引：22

作者：

DALSGAARD, A ^{[1
]}

SERICHANTALERGS, O ^{[1
]}

PITARANGSI, C ^{[1
]}

ECHEVERRIA, P ^{[1
]}

机构：

[1] ARMED FORCES RES INST MED SCI,BANGKOK 10400,THAILAND

来源：

EPIDEMIOLOGY AND INFECTION | 1995年 / 114卷 / 01期

关键词：

D O I：

10.1017/S0950268800051906

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A collection of 64 clinical and environmental Vibrio cholerae non-O1 strains isolated in Asia and Peru were characterized by molecular methods and antibiotic susceptibility testing. All strains were resistant to at least 1 and 80% were resistant to two or more antibiotics. Several strains showed multiple antibiotic resistance (greater than or equal to three antibiotics). Plasmids most often of low molecular weight were found in 21/64 (33 %) strains. The presence of plasmids did not correlate with antibiotic resistance or influence ribotype patterns. In colony hybridization studies 63/64 (98%) V. cholerae non-O1 strains were cholera toxin negative, whereas only strains recovered from patients were heat-stable enterotoxin positive. Forty-seven Bgl I ribotypes were observed. No correlation was shown between ribotype and toxin gene status. Ribotype similarity was compared by cluster analysis and two main groups of 13 and 34 ribotypes was found. Ribotyping is apparently a useful epidemiological tool in investigations of V. cholerae non-O1 infections.

引用

页码：51 / 63

页数：13

共 37 条

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