DETERMINATION OF BENZIDINE AND ITS ACETYLATED METABOLITES IN URINE BY LIQUID-CHROMATOGRAPHY

被引：25

作者：

RICE, JR

KISSINGER, PT

机构：

[1] Bioanalytical Laboratory, Department of Chemistry, Purdue University, West Lafayette, IN

来源：

JOURNAL OF ANALYTICAL TOXICOLOGY | 1979年 / 3卷 / 02期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1093/jat/3.2.64

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Methods for the analysis of benzldlne (4,4′-diamlnoblphenyl), or for benzldlne and its acotylated metabolltes, in urine are described. The procedure requires 2.0 ml of urine and involves extraction of the compound(s) followed by quantltetion via liquid chromatography with eloctrochemlcal detection (LCEC). The assay for benzidlne Is linear from 25 ng/ml to 5 μg/ml, (r = 0.090), with a precision of ± 0.06% RSD at 250 ng/ml (n = 6) and ± at 25 ng/ml (n = 5). © 1979 Oxford University Press.

引用

页码：64 / 66

页数：3

共 14 条

[1]

[Anonymous], 1974, FED REGISTER, V39, P3756

[2] Nitrosoacetylamino-derivatives of the benzene and diphenyl series [J].