STEREOCONTROLLED SYNTHESIS OF CYCLIC ETHERS BY INTRAMOLECULAR HETERO-MICHAEL ADDITION .3. ENANTIOMERIC SYNTHESIS OF HIGHLY FUNCTIONALIZED AND FUSED TETRAHYDROPYRANS

被引：35

作者：

PALAZON, JM ^{[1
]}

SOLER, MA ^{[1
]}

RAMIREZ, MA ^{[1
]}

MARTIN, VS ^{[1
]}

机构：

[1] UNIV LA LAGUNA, CTR PROD NAT ORGAN ANTONIO GONZALEZ, INST BIOORGAN, CARRETERA LA ESPERANZA 2, E-38206 LA LUGUNA, SPAIN

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 34期

关键词：

D O I：

10.1016/S0040-4039(00)73936-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A methodology based on intramolecular hetero-Michael addition of properly functionalized alkoxy-gamma-benzoyloxy-alpha,beta-unsaturated esters for the synthesis of highly substituted and fused poly-tetrahydropyran nuclei of marine polyether toxins with absolute control of all the stereocentres is described.

引用

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页码：5467 / 5470

页数：4

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