EFFICACY OF DIFFERENT REGIMENS OF INTERFERON-ALFA-2B TREATMENT IN CHRONIC HEPATITIS-C

被引:11
作者
DEBAC, C
GRIMALDI, F
CLEMENTI, C
DUCA, F
LIVOLI, D
TALIANI, G
机构
[1] Viral Hepatology Service, Institute of Tropical and Infectious Diseases, 'La Sapienza' University, Rome
关键词
D O I
10.1136/gut.34.2_Suppl.S135
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Four different dosage regimens of interferon (IFN) alfa-2b (3 million units (MU) three times weekly for three months, 3 MU three times weekly for six months, 6 MU two times weekly for six months, and 6 MU three times weekly for six months) were compared in patients with chronic hepatitis C. There was no significant difference measured by percentage of responders to treatment between the four groups, but the degree of response was inversely correlated with the severity of liver damage. Viraemia was undetectable in most (75%) of responders treated with interferon and also in 20% of those who did not respond to treatment.
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页码:S135 / S135
页数:1
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