LIMB DEFICIENCY WITH OR WITHOUT MOBIUS SEQUENCE IN 7 BRAZILIAN CHILDREN ASSOCIATED WITH MISOPROSTOL USE IN THE 1ST TRIMESTER OF PREGNANCY

被引：123

作者：

GONZALEZ, CH

VARGAS, FR

PEREZ, ABA

KIM, CA

BRUNONI, D

MARQUESDIAS, MJ

LEONE, CR

NETO, JC

LLERENA, JC

DEALMEIDA, JCC

机构：

[1] UNIV SAO PAULO,FAC MED,DEPT ORTHOPED,SAO PAULO,BRAZIL

[2] UNIV SAO PAULO,FAC MED,DEPT PEDIAT,SAO PAULO,BRAZIL

[3] ESCOLA PAULISTA MED,DEPT MORPHOL,DISCIPLINE,BR-04023 SAO PAULO,BRAZIL

[4] FIOCRUZ MS,INST FERNANDES FIGUEIRA,RIO JANEIRO,BRAZIL

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS | 1993年 / 47卷 / 01期

关键词：

PROSTAGLANDIN; VASCULAR DISRUPTION DEFECT; ABORTIFACIENT;

D O I：

10.1002/ajmg.1320470113

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Misoprostol, a synthetic analog of prostaglandin, has been widely used in Brazil as an abortifacient. Abortion is illegal in Brazil. An uncertain number of these abortion attempts are unsuccessful and the pregnancy continues. We report on 7 patients whose mothers attempted to abort using this drug in the first trimester of gestation without success. The 7 patients presented with limb defects and in 4 of them a diagnosis of Mobius sequence was made. (C) 1993 Wiley-Liss, Inc.

引用

页码：59 / 64

页数：6

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