MOLECULAR-CLONING AND CHARACTERIZATION OF THE AKLAVINONE 11-HYDROXYLASE GENE OF STREPTOMYCES-PEUCETIUS SUBSP CAESIUS ATCC-27952

被引：20

作者：

HONG, YS ^{[1
]}

HWANG, CK ^{[1
]}

HONG, SK ^{[1
]}

KIM, YH ^{[1
]}

LEE, JJ ^{[1
]}

机构：

[1] KOREA INST SCI & TECHNOL,GENET ENGN RES INST,TAEJON 305600,SOUTH KOREA

来源：

JOURNAL OF BACTERIOLOGY | 1994年 / 176卷 / 22期

关键词：

D O I：

10.1128/JB.176.22.7096-7101.1994

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

The gene encoding aklavinone 11-hydroxylase of Streptomyces peucetius subsp. caesirts ATCC 27952 was cloned and sequenced. The deduced amino acid sequence of the gene contains at least two common motifs of well-conserved amino acid sequences of several flavin-type bacterial hydroxylases. The hydroxylase gene is apparently transcribed from a single transcriptional start point. The phenotype of a dnrF mutant generated by gene disruption supports the idea that the dnrF gene encodes aklavinone 11-hydroxylase.

引用

页码：7096 / 7101

页数：6

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