COMPLEX-FORMATION OF HUMAN ALPHA-1-ANTITRYPSIN WITH COMPONENTS IN SCHISTOSOMA-MANSONI CERCARIAE

被引：9

作者：

MODHA, J ^{[1
]}

DOENHOFF, MJ ^{[1
]}

机构：

[1] UNIV COLL N WALES, SCH BIOL SCI, BANGOR LL57 2UW, GWYNEDD, WALES

来源：

PARASITE IMMUNOLOGY | 1994年 / 16卷 / 08期

基金：

英国惠康基金;

关键词：

SCHISTOSOMA-MANSONI; ALPHA-1-ANTITRYPSIN; COMPLEX FORMATION; SERINE PROTEASE INHIBITOR (SERPIN);

D O I：

10.1111/j.1365-3024.1994.tb00372.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Human alpha-1-antitrypsin (alpha 1-AT) was incubated with an extract of Schistosoma mansoni cercariae or porcine pancreatic elastase and analysed by immunoelectrophoresis and Western blotting. The inhibitor was shown to form complexes with components in S. mansoni cercariae in the same way as elastase. The role of alpha 1-AT in S. mansoni infection is discussed.

引用

页码：447 / 450

页数：4

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