THE COMPARATIVE TEA STAINING POTENTIAL OF PHENOLIC, CHLORHEXIDINE AND ANTIADHESIVE MOUTHRINSES

被引:40
作者
ADDY, M
MORAN, J
NEWCOMBE, R
WARREN, P
机构
[1] UNIV WALES COLL CARDIFF,COLL MED,DEPT COMP & MED STAT,CARDIFF,S GLAM,WALES
[2] IMPERIAL CHEM IND,DIV PHARMACEUT,MACCLESFIELD,CHESHIRE,ENGLAND
关键词
EXTRINSIC STAINING; CHLORHEXIDINE; PHENOLS; ANTIADHESIVE AGENTS; CLINICAL TRIAL;
D O I
10.1111/j.1600-051X.1995.tb01796.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Staining of teeth and mucous membranes is a well-known side-effect with chlorhexidine mouthrinses in which dietary chromogens play an important role. The purpose of this study was to determine whether a co-polymer antiadhesive agent would prevent staining by a low concentration chlorhexidine solution. Additionally, the possibility that an essential oil/phenolic rinse product may cause staining was investigated. The rinses studied were the anti-adhesive alone and combined with 0.02% chlorhexidine and the essential oil/phenolic rinse. These were positioned against a positive control rinse, 0.2% chlorhexidine, and a negative control rinse, water. The study was a single blind 5-treatment, randomised Latin square cross-over design, incorporating balance for carry-over effects. 15 volunteers participated and on Day 1 of each study period were rendered stain free by scaling and polishing of the teeth. Oral hygiene was suspended and 8x per day subjects rinsed under supervision, firstly with the allocated formulation and then with 10 ml of warm black tea. On Day 4, tooth and tongue staining was scored by area and intensity (colour). A washout period of at least 3 1/2 days was permitted between treatment periods when oral hygiene was resumed. Before the study and during washouts, volunteers practised tongue brushing. Tooth and tongue staining was significantly increased with 0.2% chlorhexidine compared to the essential oil/phenolic rinse which in turn was significantly increased compared to the other 3 rinses. The antiadhesive/chlorhexidine rinse produced no more staining than the anti-adhesive or water rinse. However, the parallel plaque regrowth study suggests this inhibition of staining resulted from the vitiation of the chlorhexidine activity by the antiadhesive. The methodology would appear a simple and quick way of assessing the propensity of mouthrinses to cause extrinsic staining.
引用
收藏
页码:923 / 928
页数:6
相关论文
共 24 条
[1]   EFFECT OF TOOTHPASTE RINSES COMPARED WITH CHLORHEXIDINE ON PLAQUE-FORMATION DURING A 4-DAY PERIOD [J].
ADDY, M ;
WILLIS, L ;
MORAN, J .
JOURNAL OF CLINICAL PERIODONTOLOGY, 1983, 10 (01) :89-99
[2]   COMPARISON OF THE BISBIGUANIDE ANTISEPTICS ALEXIDINE AND CHLORHEXIDINE .2. CLINICAL AND INVITRO STAINING PROPERTIES [J].
ADDY, M ;
ROBERTS, WR .
JOURNAL OF CLINICAL PERIODONTOLOGY, 1981, 8 (03) :220-230
[3]   INVITRO STUDY OF THE ROLE OF DIETARY FACTORS IN THE ETIOLOGY OF TOOTH STAINING ASSOCIATED WITH THE USE OF CHLORHEXIDINE [J].
ADDY, M ;
PRAYITNO, S ;
TAYLOR, L ;
CADOGAN, S .
JOURNAL OF PERIODONTAL RESEARCH, 1979, 14 (05) :403-410
[4]   EXTRINSIC TOOTH DISCOLORATION BY METALS AND CHLORHEXIDINE .1. SURFACE PROTEIN DENATURATION OR DIETARY PRECIPITATION [J].
ADDY, M ;
MORAN, J ;
GRIFFITHS, AA ;
WILLSWOOD, NJ .
BRITISH DENTAL JOURNAL, 1985, 159 (09) :281-285
[5]  
ADDY M, 1989, Clinical Preventive Dentistry, V11, P10
[6]   THE USE OF POLYMETHYLMETHACRYLATE TO COMPARE THE ADSORPTION AND STAINING REACTIONS OF SOME CATIONIC ANTISEPTICS [J].
ADDY, M ;
ROBERTS, WR .
JOURNAL OF PERIODONTOLOGY, 1981, 52 (07) :380-385
[7]  
ADDY M, 1993, J DENT RES, V72, P919
[8]  
ADDY M, 1985, BR DENT J, V159, P335
[9]   CHEMICAL PLAQUE CONTROL AND EXTRINSIC TOOTH DISCOLORATION - A REVIEW OF POSSIBLE MECHANISMS [J].
ERIKSEN, HM ;
NORDBO, H ;
KANTANEN, H ;
ELLINGSEN, JE .
JOURNAL OF CLINICAL PERIODONTOLOGY, 1985, 12 (05) :345-350
[10]  
FLOTRA L, 1971, Scandinavian Journal of Dental Research, V79, P119