SYNTHESIS OF 6-AZACHOLESTEN-3-ONES - POTENT INHIBITORS OF 5-ALPHA-REDUCTASE

被引：24

作者：

HAFFNER, C

机构：

[1] Glaxo Inc. Research Institute Five Moore Dr., Research Triangle Park

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 23期

关键词：

D O I：

10.1016/0040-4039(95)00711-K

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-Cholesten-3-one was converted into 6-azacholesten-3-ones (7, 14 and 15). These compounds proved to be potent inhibitors of both type 1 and 2 human 5 alpha-reductase.

引用

页码：4039 / 4042

页数：4

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