MYOGENIC STROMAL TUMOR OF THE MALE BREAST (SO-CALLED MYOFIBROBLASTOMA)

被引:33
作者
BEGIN, LR [1 ]
机构
[1] SIR MORTIMER B DAVIS JEWISH HOSP, MONTREAL H3T 1E2, QUEBEC, CANADA
关键词
BREAST; MALE BREAST; MYOFIBROBLASTOMA; STROMAL TUMOR;
D O I
10.3109/01913129109023191
中图分类号
TH742 [显微镜];
学科分类号
摘要
A case of a distinctive stromal tumor of the male breast, recently designated as myofibroblastoma, is reported. A fascicular clustering of spindle cells with intervening hyaline bands was the dominant pattern, but areas of myxoid transformation were present. Ultrastructure revealed a large predominance of fibroblastlike cells, often containing dispersed or aggregated intermediate and/or thin filaments. These cells depicted numerous thin processes encircling collagenous bundles. Primitive mesenchymal and typical smooth muscle cells were present, but myofibroblasts were not identified. Vimentin was diffusely expressed, whereas desmin and muscle-specific actin were detected in, respectively, 50% to 60% and 15% to 25% of the cell population. The designation of myogenic stromal tumor is, therefore, considered more appropriate.
引用
收藏
页码:613 / 622
页数:10
相关论文
共 13 条
[1]  
Begin L. R., 1989, SURG PATHOL, V2, P151
[2]   INFILTRATING MYOEPITHELIOMA OF THE BREAST [J].
ERLANDSON, RA ;
ROSEN, PP .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1982, 6 (08) :785-793
[3]  
SCHURCH W, 1985, ULTRASTRUCT PATHOL, V8, P1
[4]  
Seemayer T A, 1980, Pathol Annu, V15, P443
[5]  
SKALLI O, 1989, LAB INVEST, V60, P275
[6]   INTRANODAL HEMORRHAGIC SPINDLE-CELL TUMOR WITH AMIANTHOID FIBERS - REPORT OF 6 CASES OF A DISTINCTIVE MESENCHYMAL NEOPLASM OF THE INGUINAL REGION THAT SIMULATES KAPOSIS SARCOMA [J].
SUSTER, S ;
ROSAI, J .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1989, 13 (05) :347-357
[7]  
TOKER C, 1981, CANCER, V48, P1615, DOI 10.1002/1097-0142(19811001)48:7<1615::AID-CNCR2820480724>3.0.CO
[8]  
2-I
[9]   MYOFIBROBLASTOMA OF THE BREAST - 16 CASES OF A DISTINCTIVE BENIGN MESENCHYMAL TUMOR [J].
WARGOTZ, ES ;
WEISS, SW ;
NORRIS, HJ .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1987, 11 (07) :493-502
[10]  
WEIDNER N, 1988, CANCER, V62, P1561, DOI 10.1002/1097-0142(19881015)62:8<1561::AID-CNCR2820620817>3.0.CO