DISTRIBUTION OF D(5) DOPAMINE RECEPTOR MESSENGER-RNA IN RAT-BRAIN

被引：129

作者：

MEADORWOODRUFF, JH ^{[1
]}

MANSOUR, A ^{[1
]}

GRANDY, DK ^{[1
]}

DAMASK, SP ^{[1
]}

CIVELLI, O ^{[1
]}

WATSON, SJ ^{[1
]}

机构：

[1] OREGON HLTH SCI UNIV, VOLLUM INST ADV BIOMED RES, PORTLAND, OR 97201 USA

来源：

NEUROSCIENCE LETTERS | 1992年 / 145卷 / 02期

关键词：

RECEPTOR; DOPAMINE; RNA; MESSENGER; CATECHOLAMINE;

D O I：

10.1016/0304-3940(92)90024-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The distribution of the messenger RNA encoding the dopamine D5 receptor was determined in the rat brain by in situ hybridization. Using [S-35]-labelled riboprobes to either the rat or human D5 receptor, this mRNA was localized to the hippocampus and the parafascicular nucleus of the thalamus. This mRNA could not be visualized in the more traditional brain regions associated with dopaminergic cell bodies or projection fields. This unusual distribution suggests a novel function in the brain for this subtype of the dopamine receptor.

引用

页码：209 / 212

页数：4

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