EPIGENETIC INHERITANCE IN MAMMALS

被引：54

作者：

LYON, MF

机构：

[1] MRC Radiobiology Unit, Chilton, Didcot

来源：

TRENDS IN GENETICS | 1993年 / 9卷 / 04期

关键词：

D O I：

10.1016/0168-9525(93)90206-W

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The epigenetic phenomena of genome imprinting and X-chromosome inactivation, found in mammals, both entail homologous genes or chromosomes behaving differently within the same cell. Although both have consequences for genic balance in the whole genome, in imprinting the control seems mainly at the single gene level, whereas in X-chromosome inactivation there is coordinated regulation of the whole chromosome, and single gene effects are relatively minor.

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页码：123 / 128

页数：6

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