RELEASE CHARACTERISTICS OF IBUPROFEN FROM EXCIPIENT-LOADED ALGINATE GEL BEADS

被引：46

作者：

HWANG, SJ ^{[1
]}

RHEE, GJ ^{[1
]}

LEE, KM ^{[1
]}

OH, KH ^{[1
]}

KIM, CK ^{[1
]}

机构：

[1] SEOUL NATL UNIV,COLL PHARM,KWANAK GU,SEOUL 151742,SOUTH KOREA

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1995年 / 116卷 / 01期

关键词：

ALGINATE BEAD; IBUPROFEN; EXCIPIENT; IN VITRO RELEASE;

D O I：

10.1016/0378-5173(94)00281-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Ibuprofen-loaded alginate beads were prepared and found to optimize in vitro release with zero-order kinetics. The release of ibuprofen could be controlled by adding excipients or by adjusting the NaAlg/ibuprofen ratio.

引用

页码：125 / 128

页数：4

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