SYNTHESIS OF PEPTIDES CONTAINING ALPHA,ALPHA-DISUBSTITUTED ALPHA-AMINO-ACIDS BY THE AZIRINE OXAZOLONE METHOD - THE (12-20)-NONAPEPTIDE OF THE IONOPHORE ALAMETHICIN

被引：64

作者：

WIPF, P ^{[1
]}

HEIMGARTNER, H ^{[1
]}

机构：

[1] UNIV ZURICH, INST ORGAN CHEM, WINTERTHURERSTR 190, CH-8057 ZURICH, SWITZERLAND

来源：

HELVETICA CHIMICA ACTA | 1990年 / 73卷 / 01期

关键词：

D O I：

10.1002/hlca.19900730103

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The (12–20)‐nonapeptide Z‐Leu‐Aib‐Pro‐Val‐Aib‐Aib‐Glu (OBzl)‐Gln‐Pheol (10) of the ionophor alamethicin was synthesized by a new strategy, using 3‐amino‐2,2‐dimethyl‐2H‐azirines 2 as synthons for the α‐aminoisobutyric acid (Aib) moieties. Copyright © 1990 Verlag GmbH & Co. KGaA, Weinheim

引用

页码：13 / 24

页数：12

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