THE SEARCH FOR THE FAMILIAL BREAST OVARIAN-CANCER GENE

被引：39

作者：

BLACK, DM

SOLOMON, E

机构：

来源：

TRENDS IN GENETICS | 1993年 / 9卷 / 01期

基金：

澳大利亚研究理事会;

关键词：

D O I：

10.1016/0168-9525(93)90068-S

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Familial breast cancer is a very common autosomal dominant disorder in women A predisposing gene for breast and ovarian cancer (BRCA1) bas been mapped by linkage analysis to the long arm of chromosome 17. In almost all families with breast and ovarian cancer and half of those with only breast cancer, the disease is linked to this gene. The BRCA1 gene, which is also believed to be involved in sporadic breast and ovarian cancer, should soon be identified

引用

页码：22 / 26

页数：5

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