THE EUROPEAN SPINE PHANTOM - A TOOL FOR STANDARDIZATION AND QUALITY-CONTROL IN SPINAL BONE-MINERAL MEASUREMENTS BY DXA AND QCT

被引:211
作者
KALENDER, WA
FELSENBERG, D
GENANT, HK
FISCHER, M
DEQUEKER, J
REEVE, J
机构
[1] Institut für Medizinische Physik, Universität Erlangen, 91054 Erlangen
[2] Department of Radiology, Klinikum Benjamin Franklin, Berlin
[3] Department of Radiology, University of California, San Francisco, CA
[4] Department of Nuclear Medicine, Städt. Kliniken, Kassel
[5] Department of Rheumatology, University of Leuven, Leuven
[6] Institute of Public Health, University of Cambridge, Cambridge
关键词
MEASUREMENT; SPINAL BONE MINERALS; DXA AND QCT; STANDARDIZATION; QUALITY CONTROL; OSTEOPOROSIS;
D O I
10.1016/0720-048X(95)00631-Y
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The lack of standardization in bone mineral measurements of the lumbar spine and other skeletal sites is generally recognized as an important and unresolved issue, We report and discuss efforts at standardization and cross-calibration of DXA and QCT equipment, We have designed and tested a geometrically defined, semi-anthropomorphic phantom, the European Spine Phantom (ESP), It contains a spine insert consisting of three vertebrae of increasing bone mineral densities and thicknesses of cortical structures; the respective parameters are given in tabular form for the final phantom design, Results for cross-calibration with the ESP compare well with patient results. Measurements on the first 30 phantoms confirmed that the ESP can be manufactured with a variation of about 1%. We conclude that the ESP is suitable for daily quality assurance, cross-calibration of instruments and universal standardization. The ESP was used to establish standardized BMD (sBMD) units for DXA equipment going into effect in late 1995. Its acceptance by manufacturers as a calibration standard for DXA and QCT measurements appears imminent,
引用
收藏
页码:83 / 92
页数:10
相关论文
共 28 条
[1]  
Cummings, Kelsey, Nevitt, O'Dowd, Epidemiology of osteoporosis and osteoporotic fractures, Epidemiol Rev, 7, (1958)
[2]  
Genant, Block, Steiger, Gluer, Ettinger, Harris, Appropriate use of bone densitometry, Radiology, 170, pp. 817-822, (1989)
[3]  
Schild, Heller, Osteoporose, (1992)
[4]  
Kelly, Slovik, Neer, Calibration and standardization of bone mineral densitometry, J Bone Miner Res, 4, pp. 663-669, (1989)
[5]  
Genant, Grampp, Gluer, Faulkner, Jergas, Engelke, Hagiwara, van Kuijk, Universal standardization for dual X-ray absorptiometry: patient and phantom cross-calibration results, J Bone Miner Res, 9, pp. 1503-1514, (1994)
[6]  
Dequeker, Reeve, Pearson, Bright, Felsenberg, Kalender, Langton, Laval-Jeantet, Ruegsegger, Van der Perre, Multicentre European COMAC-BME study on the standardization of bone densitometry procedures, Technol Health Care, 1, pp. 127-131, (1993)
[7]  
Laskey, Flaxman, Barber, Trafford, Hayball, Lyttle, Crisp, Compston, Comparative performance in vitro and in vivo of Lunar DPX and Hologic QDR-1000 dual energy X-ray absorptiometers, Br J Radiol, 64, pp. 1023-1029, (1991)
[8]  
Kalender, Fischer, Quality control and standardisation of absorptiometric and computer tomographic measurements of bone mineral mass and density, Radiat Prot Dosimetry, 49, pp. 229-233, (1993)
[9]  
Pearson, Dequeker, Henley, Bright, Reeve, Kalender, Laval-Jeantet, Ruegsegger, Felsenberg, Adams, Et al., European semi-anthropomorphic spine phantom for the calibration of bone densitometers, Assessment of precision stability and accuracy, (1994)
[10]  
Morita, Orimo, Yamamoto, Fukunaga, Shiraki, Et al., Some problems of dual-energy X-ray absorptiometry in the clinical use, Osteoporosis Int, 1, pp. 87-90, (1993)