HL-A ANTIGENS AND GENES .I. A STUDY OF UNRELATED NORWEGIANS

被引：24

作者：

THORSBY, E

机构：

[1] Blood Bank, Department of Immunohaematology, U11Evål Hospital, Oslo

来源：

VOX SANGUINIS | 1969年 / 17卷 / 02期

关键词：

D O I：

10.1111/j.1423-0410.1969.tb00377.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Summary. To obtain information about the genetic basis of the HL‐A system, 299 unrelated Norwegians were examined with HL‐A antisera. The results indicated that the HL‐A antigens are determined by multiple mutually exclusive genes at two sub‐loci, the LA sub‐locus and the 4 sub‐locus. Four alleles could be identified at the LA sub‐locus: LA1, LA2, LA3 and LA‐BS. Additional alleles exist at this sub‐locus, with a frequency of 0.2572 in this material. Five alleles were found at the 4 sub‐locus: MH, TT, HN, 7C and 7D. Additional alleles also exist at this sub‐locus; the frequency of this ‘null’ allele was calculated to be 0.4565. © 1969 Blackwell Publishing Ltd

引用

页码：81 / &

共 18 条

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