USER-FRIENDLY METHOD FOR RAPID BRAIN AND CSF VOLUME CALCULATION USING TRANSAXIAL MRI IMAGES

被引：19

作者：

HARRIS, GJ

RHEW, EH

NOGA, T

PEARLSON, GD

机构：

[1] JOHNS HOPKINS MED INST,DEPT PSYCHIAT,DIV PSYCHIAT NEUROIMAGING,BALTIMORE,MD 21205

[2] JOHNS HOPKINS MED INST,DEPT PSYCHIAT,DIV NEUROIMAGING,BALTIMORE,MD 21205

来源：

PSYCHIATRY RESEARCH-NEUROIMAGING | 1991年 / 40卷 / 01期

关键词：

BRAIN VOLUME; CEREBROSPINAL FLUID PERCENTAGE; COMPUTER METHODS; MAGNETIC RESONANCE IMAGING;

D O I：

10.1016/0925-4927(91)90029-P

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A reliable computer method was developed for straightforward, rapid determination of whole brain and cerebrospinal fluid (CSF) volumes from a set of contiguous transaxial magnetic resonance images. The semiautomatic algorithm used a threshold-guided edge follower. Subtraction of proton-weighted from T2-weighted images was used to highlight CSF. Phantom studies were used for validity assessment. Interrater and intrarater reliability and correlation with manual measurement were excellent. Percent CSF and brain volumes were determined for small groups of Alzheimer's disease, HIV seropositive, obsessive-compulsive disorder, and schizophrenic patients as well as for young and elderly normal controls.

引用

页码：61 / 68

页数：8

共 22 条

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