OPTIMIZATION OF NMR AND HPLC CONDITIONS FOR LC-NMR

被引:28
作者
GRIFFITHS, L
机构
[1] Pharmaceutical Department, ZENECA Pharmaceuticals, Hurdsfield Industrial Estate, Macclesfield
关键词
D O I
10.1021/ac00118a010
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The NMR sensitivity was recognized as the major issue in the optimization of the coupled HPLC-NMR experiment, Each of the relevant interactions between HPLC parameters and NMR parameters has been examined in detail, such that workers should be able to design a strategy to optimize their own experiments.
引用
收藏
页码:4091 / 4095
页数:5
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