IDENTIFICATION OF THE MUTATIONS IN THE PRFB GENE OF ESCHERICHIA-COLI K12, WHICH CONFER UGA SUPPRESSOR ACTIVITY

被引：8

作者：

WU, ED ^{[1
]}

INOKUCHI, H ^{[1
]}

OZEKI, H ^{[1
]}

机构：

[1] KYOTO UNIV,FAC SCI,DEPT BIOPHYS,SAKYO KU,KYOTO 606,JAPAN

来源：

JAPANESE JOURNAL OF GENETICS | 1990年 / 65卷 / 03期

关键词：

D O I：

10.1266/jjg.65.115

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

By DNA sequencing and gene dissection, it has been revealed that S u+ UGA #11, the mutant prfB of E. coli (Chang et al, 1990) has a double mutation compared with the wild-type LS653: one is a base substitution from T to C at the codon 63 and the other is from G to A at the codon 79. Both mutations cause amino acid substitution, Leu63→Phe63 (L63F) and Asp79→Gly79 (D79G), and are necessary to confer the efficient UGA suppressor activity. © 1990, The Genetics Society of Japan. All rights reserved.

引用

页码：115 / 119

页数：5

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