IMMUNODEFICIENCY IN EPILEPSY - NEW VIEW

被引：10

作者：

FONTANA, A ^{[1
]}

GROB, PJ ^{[1
]}

机构：

[1] UNIV ZURICH, KANTONSSPITAL, DEPT MED, CLIN IMMUNOL SECT, CH-8091 ZURICH, SWITZERLAND

来源：

JOURNAL OF NEUROLOGY | 1979年 / 220卷 / 04期

关键词：

Epilepsy; Hydantoins; IgA deficiency;

D O I：

10.1007/BF00314154

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Up to 12% of epileptic patients have subnormal Ig[immunoglobulin]A serum concentrations. IgA deficiency is probably correlated with hydantoin treatment and also with the type of seizure. In a followup study, IgA deficiency in epileptics was a rather constant feature of a given patient. The most pronounced changes in IgA levels were seen in patients in whom the hydantoin medication also changed. Low IgA levels were also reported in untreated epileptics. A new classification for the immunodeficiency state in epileptics is introduced.

引用

页码：297 / 301

页数：5

共 10 条

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[4]

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[5]

FONTANA A, 1976, LANCET, V2, P228

[6] IMMUNOLOGICAL ABNORMALITIES AND HLA ANTIGEN FREQUENCIES IN IGA DEFICIENT PATIENTS WITH EPILEPSY [J].

FONTANA, A ;

JOLLER, H ;

SKVARIL, F ;

GROB, P .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1978, 41 (07) :593-597

[7] IMMUNOGLOBULIN ABNORMALITIES IN RELATIVES OF IGA DEFICIENT EPILEPTICS [J].

FONTANA, A ;

GROB, PJ ;

SAUTER, R .

JOURNAL OF NEUROLOGY, 1978, 217 (03) :207-212

[8]

Horowitz S, 1975, Birth Defects Orig Artic Ser, V11, P129

[9]

SEAGER J, 1975, LANCET, V2, P632

[10]

STANWORTH DR, 1977, LANCET, V1, P1001

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