SULFATED POLYANIONS DO NOT INHIBIT DUCK HEPATITIS-B VIRUS-INFECTION

被引：13

作者：

OFFENSPERGER, WB ^{[1
]}

OFFENSPERGER, S ^{[1
]}

WALTER, E ^{[1
]}

BLUM, HE ^{[1
]}

GEROK, W ^{[1
]}

机构：

[1] HARVARD UNIV,MASSACHUSETTS GEN HOSP,SCH MED,CTR CANC,GASTROINTESTINAL UNIT,BOSTON,MA 02129

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1991年 / 35卷 / 11期

关键词：

D O I：

10.1128/AAC.35.11.2431

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

On the basis of the antiviral action of sulfated polyanions in human immunodeficiency virus and other viral infections, we studied the effect of dextran sulfate and heparin on duck hepatitis B virus infection. These agents do not affect viral uptake and replication in liver cells in vitro or in vivo. Sulfated polyanions, therefore, appear to have no potential for the treatment of hepadnavirus infections.

引用

页码：2431 / 2433

页数：3

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