THE BIOSYNTHESIS OF TETRAKETIDES - ENZYMOLOGY, MECHANISM AND MOLECULAR PROGRAMMING

[1] THE MULTIFUNCTIONAL 6-METHYLSALICYLIC ACID SYNTHASE GENE OF PENICILLIUM-PATULUM - ITS GENE STRUCTURE RELATIVE TO THAT OF OTHER POLYKETIDE SYNTHASES [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1990, 192 (02): : 487 - 498

[2] 6-DEOXYERYTHRONOLIDE-B SYNTHASE-2 FROM SACCHAROPOLYSPORA-ERYTHRAEA - CLONING OF THE STRUCTURAL GENE, SEQUENCE-ANALYSIS AND INFERRED DOMAIN-STRUCTURE OF THE MULTIFUNCTIONAL ENZYME [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1992, 204 (01): : 39 - 49

[3] Bu'Lock J. D., 1979, COMPREHENSIVE ORGANI, V5, P927

[4] CHATER KF, 1990, BIO-TECHNOL, V8, P115, DOI 10.1038/nbt0290-115

[5] AN UNUSUALLY LARGE MULTIFUNCTIONAL POLYPEPTIDE IN THE ERYTHROMYCIN-PRODUCING POLYKETIDE SYNTHASE OF SACCHAROPOLYSPORA-ERYTHRAEA [J]. NATURE, 1990, 348 (6297) : 176 - 178

[6] DEWICK PLM, 1989, NAT PROD REP, V2, P149

[7] BIOSYNTHESIS OF 6-METHYLSALICYLIC ACID [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1970, 13 (01): : 98 - &

[8] MODULAR ORGANIZATION OF GENES REQUIRED FOR COMPLEX POLYKETIDE BIOSYNTHESIS [J]. SCIENCE, 1991, 252 (5006) : 675 - 679

[9] MOLECULAR-GENETICS OF POLYKETIDES AND ITS COMPARISON TO FATTY-ACID BIOSYNTHESIS [J]. ANNUAL REVIEW OF GENETICS, 1990, 24 : 37 - 66

[10] STEREOSPECIFIC MANIPULATION OF HYDROGEN-ATOMS WITH OPPOSITE ABSOLUTE ORIENTATIONS DURING THE BIOSYNTHESIS OF THE POLYKETIDE 6-METHYLSALICYLIC ACID FROM CHIRAL MALONATES IN PENICILLIUM-PATULUM [J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1990, (03) : 238 - 242

[1] THE MULTIFUNCTIONAL 6-METHYLSALICYLIC ACID SYNTHASE GENE OF PENICILLIUM-PATULUM - ITS GENE STRUCTURE RELATIVE TO THAT OF OTHER POLYKETIDE SYNTHASES [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1990, 192 (02): : 487 - 498

[2] 6-DEOXYERYTHRONOLIDE-B SYNTHASE-2 FROM SACCHAROPOLYSPORA-ERYTHRAEA - CLONING OF THE STRUCTURAL GENE, SEQUENCE-ANALYSIS AND INFERRED DOMAIN-STRUCTURE OF THE MULTIFUNCTIONAL ENZYME [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1992, 204 (01): : 39 - 49

[3] Bu'Lock J. D., 1979, COMPREHENSIVE ORGANI, V5, P927

[4] CHATER KF, 1990, BIO-TECHNOL, V8, P115, DOI 10.1038/nbt0290-115

[5] AN UNUSUALLY LARGE MULTIFUNCTIONAL POLYPEPTIDE IN THE ERYTHROMYCIN-PRODUCING POLYKETIDE SYNTHASE OF SACCHAROPOLYSPORA-ERYTHRAEA [J]. NATURE, 1990, 348 (6297) : 176 - 178

[6] DEWICK PLM, 1989, NAT PROD REP, V2, P149

[7] BIOSYNTHESIS OF 6-METHYLSALICYLIC ACID [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1970, 13 (01): : 98 - &

[8] MODULAR ORGANIZATION OF GENES REQUIRED FOR COMPLEX POLYKETIDE BIOSYNTHESIS [J]. SCIENCE, 1991, 252 (5006) : 675 - 679

[9] MOLECULAR-GENETICS OF POLYKETIDES AND ITS COMPARISON TO FATTY-ACID BIOSYNTHESIS [J]. ANNUAL REVIEW OF GENETICS, 1990, 24 : 37 - 66

[10] STEREOSPECIFIC MANIPULATION OF HYDROGEN-ATOMS WITH OPPOSITE ABSOLUTE ORIENTATIONS DURING THE BIOSYNTHESIS OF THE POLYKETIDE 6-METHYLSALICYLIC ACID FROM CHIRAL MALONATES IN PENICILLIUM-PATULUM [J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1990, (03) : 238 - 242