REGULATION OF THE SYNTHESIS OF ADENYLATE-CYCLASE IN ESCHERICHIA-COLI BY THE CAMP-CAMP RECEPTOR PROTEIN COMPLEX

被引：40

作者：

MAJERFELD, IH

MILLER, D

SPITZ, E

RICKENBERG, HV

机构：

[1] NATL JEWISH HOSP & RES CTR, DEPT MOLEC & CELLULAR BIOL, DENVER, CO 80206 USA

[2] UNIV COLORADO, SCH MED, DEPT BIOCHEM BIOPHYS & GENET, DENVER, CO 80206 USA

来源：

MOLECULAR AND GENERAL GENETICS | 1981年 / 181卷 / 04期

关键词：

D O I：

10.1007/BF00428738

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The synthesis of adenylate cyclase (ATP pyrophosphatelyase-(cyclizing), E.C. 4.6.1.1) in E. coli appears to be regulated negatively by the cAMP receptor protein, CRP. This conclusion is based on a comparison of adenylate cyclase activities measured in vitro with the rates of cAMP synthesis by intact bacteria. The activity of adenylate cyclase, depending on conditions of growth, is also regulated by CRP; this effect is indirect insofar as it is mediated by a protein or proteins under CRP control.

引用

页码：470 / 475

页数：6

共 32 条

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