INVESTIGATION OF INTERMEDIATE STEPS IN BIOSYNTHESIS OF ECDYSTERONE FROM CHOLESTEROL IN PODOCARPUS ELATA

被引：15

作者：

JOLY, RA

SVAHN, CM

BENNETT, RD

HEFTMANN, E

机构：

[1] Division of Biology, California Institute of Technology, Pasadena, CA

[2] Western Regional Research Laboratory,2 2 A laboratory of the Western Utilization Research and Development Division, Agricultural Research Service, U.S. Department of Agriculture. Work conducted under a cooperative agreement with the California Institute of

来源：

PHYTOCHEMISTRY | 1969年 / 8卷 / 10期

关键词：

D O I：

10.1016/S0031-9422(00)88076-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Both 4-14C- and 26-14C-cholesterol were incorporated into ecdysterone by Podocarpus elata. This demonstrates that no degradation of the side chain is involved in the biosynthetic pathway. However, three possible intermediates in ecdysterone biosynthesis, 25-hydroxycholesterol-26-14C, cholesterol 5α,6α-epoxide-4-14C, and cholesterol 5β,6β-epoxide-4-14C were not converted to ecdysterone. The significance of these results in the biosynthesis of ecdysterone is discussed. © 1970.

引用

页码：1917 / &

共 8 条

[1]

BENNETT RAYMOND D., 1965, PHYTOCHEMISTRY, V4, P475, DOI 10.1016/S0031-9422(00)86199-3

[2] PROGESTERONE METABOLISM IN DIGITALIS LANATA [J].