CYCLOSPORIN-A - IMMUNOSUPPRESSIVE AGENT PREFERENTIALLY ACTIVE AGAINST PROLIFERATING T-CELLS

被引：249

作者：

WHITE, DJG

PLUMB, AM

PAWELEC, G

BRONS, G

机构：

[1] Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Cambridge

来源：

TRANSPLANTATION | 1979年 / 27卷 / 01期

关键词：

D O I：

10.1097/00007890-197901000-00014

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The in vitro action of the immunosuppressive agent Cyclos-pirin A has been investigated using porcine cells. Lymphocyte proliferation induced in response to transplantation antigens and phytohaemagglutinin (PHA) was inhibited by this agent at doses that failed to inhibit mitogenisis in response to sheep anti-pig IgM, growth of kidney cell monolayers, and leukocyte migration. © 1979 by The Williams & Wilkins Co.

引用

页码：55 / 58

页数：4

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