MORPHOLOGICAL-CHANGES IN THE HUMAN AMNION EPITHELIUM THAT ACCOMPANY LABOR AS SEEN WITH SCANNING AND TRANSMISSION ELECTRON-MICROSCOPY

被引:9
作者
SONEK, J [1 ]
GABBE, SG [1 ]
IAMS, JD [1 ]
KNISS, DA [1 ]
机构
[1] OHIO STATE UNIV,COLL MED,DEPT OBSTET & GYNECOL,DIV MATERNAL FETAL MED,COLUMBUS,OH 43210
关键词
PARTURITION; ULTRASTRUCTURE; AMNION EPITHELIUM; ELECTRON MICROSCOPY;
D O I
10.1016/0002-9378(91)90679-L
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Scanning and transmission electron microscopy were used to assess the influence of normal, active labor on the ultrastructure of the human amnion epithelial membrane. Amnion membranes (reflected and placental portions) were obtained from patients either in active labor who were delivered vaginally or by cesarean section after 6 to 12 hours of labor or from patients who underwent elective cesarean section before clinical signs of overt labor. Scanning electron microscopy revealed that reflected amnion membranes that were obtained from patients who were not in labor consisted of a uniform single layer of epithelial cells with numerous microvilli on the apical surface and closely associated cellular borders. In contrast, amnion membranes that were obtained from patients who were in labor consisted of a single layer of epithelial cells, which was interupted by wide intercellular gaps and extracellular extrusions. Transmission electron microscopy showed that intercellular junctions tended to be less complex in patients who were in labor versus patients who were not in labor. Although lipid droplets were prevalent in both patient groups, specimens that were obtained from patients who were in labor had more lipid droplets per cell than specimens from patients who were not in labor. These results support the theory that the complex biochemical events that culminate in parturition are accompanied and/or preceded by demonstrable morphologic changes in the amnion membrane.
引用
收藏
页码:1174 / 1180
页数:7
相关论文
共 10 条
[1]  
APLIN JD, 1985, J CELL SCI, V79, P119
[2]   VACUOLATION IN HUMAN AMNION CELL STUDIED BY TIME-LAPSE PHOTOGRAPHY AND ELECTRON MICROSCOPY [J].
ARMSTRONG, WD ;
WILT, JC ;
PRITCHARD, ET .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1968, 102 (07) :932-+
[3]   THE MICROSCOPIC ANATOMY OF THE HUMAN AMNION AND CHORION [J].
BOURNE, GL .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1960, 79 (06) :1070-1073
[4]   THE MICROSCOPIC ANATOMY OF THE FETAL MEMBRANES WITH PARTICULAR REFERENCE TO THE DETAILED STRUCTURE OF THE AMNION [J].
DANFORTH, DN ;
HULL, RW .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1958, 75 (03) :536-550
[5]   DISTRIBUTION AND CHARACTERIZATION OF ANIONIC SITES IN THE BASAL LAMINA OF DEVELOPING HUMAN AMNIOTIC EPITHELIUM [J].
KING, BF .
ANATOMICAL RECORD, 1985, 212 (01) :57-62
[6]   INITIATION OF HUMAN PARTURITION .12. BIOSYNTHESIS AND METABOLISM OF PROSTAGLANDINS IN HUMAN-FETAL MEMBRANES AND UTERINE DECIDUA [J].
OKAZAKI, T ;
CASEY, ML ;
OKITA, JR ;
MACDONALD, PC ;
JOHNSTON, JM .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1981, 139 (04) :373-381
[7]  
OKITA JR, 1982, J BIOL CHEM, V257, P4029
[8]  
OKITA JR, 1983, IN VITRO CELL DEV B, V19, P117
[9]   MICROANATOMY OF HUMAN AMNIOTIC MEMBRANES - LIGHT MICROSCOPIC, TRANSMISSION, AND SCANNING ELECTRON-MICROSCOPIC STUDY [J].
VANHERENDAEL, BJ ;
OBERTI, C ;
BROSENS, I .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1978, 131 (08) :872-880
[10]  
WYNN RM, 1968, OBSTET GYNECOL, V31, P759