INVESTIGATION OF THE NONLINEAR ASPECTS OF IMAGING THROUGH A HIGHLY SCATTERING MEDIUM

被引:11
作者
HASELGROVE, JC [1 ]
WANG, NG [1 ]
CHANCE, B [1 ]
机构
[1] UNIV PENN,SCH MED,DEPT BIOCHEM,PHILADELPHIA,PA 19104
关键词
PHOTON MIGRATION; PHOTON DIFFUSION; OPTICAL IMAGING; EDGE-SPREAD FUNCTION; TIMES-OF-FLIGHT;
D O I
10.1118/1.596875
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The edge-spread function that is expected when imaging a sharp edge in a highly scattering medium using a time-of-flight imaging system has been investigated. Experimental results have been compared with computer simulations. The effect of scattering is to broaden the image of the edge, accompanied by an offset of the midpoint (50% transmission) of the edge. Small random errors in the measurement of the time of flight results in an increase in the offset of the edge position at very short times of flight. The offset in the midpoint of the edge is evidence of the nonlinear nature imaging process, in view of which we conclude that nonlinear algorithms will be necessary to maximize the image information available from measured intensities.
引用
收藏
页码:17 / 23
页数:7
相关论文
共 18 条
  • [1] OPTICAL PROPAGATION IN TISSUE WITH ANISOTROPIC SCATTERING
    ARNFIELD, MR
    TULIP, J
    MCPHEE, MS
    [J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1988, 35 (05) : 372 - 381
  • [2] COMPARISON OF TIME-RESOLVED AND TIME-UNRESOLVED MEASUREMENTS OF DEOXYHEMOGLOBIN IN BRAIN
    CHANCE, B
    LEIGH, JS
    MIYAKE, H
    SMITH, DS
    NIOKA, S
    GREENFELD, R
    FINANDER, M
    KAUFMANN, K
    LEVY, W
    YOUNG, M
    COHEN, P
    YOSHIOKA, H
    BORETSKY, R
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (14) : 4971 - 4975
  • [3] TIME-RESOLVED SPECTROSCOPY OF HEMOGLOBIN AND MYOGLOBIN IN RESTING AND ISCHEMIC MUSCLE
    CHANCE, B
    NIOKA, S
    KENT, J
    MCCULLY, K
    FOUNTAIN, M
    GREENFELD, R
    HOLTOM, G
    [J]. ANALYTICAL BIOCHEMISTRY, 1988, 174 (02) : 698 - 707
  • [4] Chance B, 1989, PHOTON MIGRATION TIS
  • [5] DELPY DT, 1988, PHYS MED BIOL, V33, P1422
  • [6] TOTAL ATTENUATION COEFFICIENTS AND SCATTERING PHASE FUNCTIONS OF TISSUES AND PHANTOM MATERIALS AT 633-NM
    FLOCK, ST
    WILSON, BC
    PATTERSON, MS
    [J]. MEDICAL PHYSICS, 1987, 14 (05) : 835 - 841
  • [7] GROENHUIS RAJ, 1989, APPL OPTICS, V28, P2463
  • [8] TRANSILLUMINATION IMAGING PERFORMANCE - A TIME-OF-FLIGHT IMAGING-SYSTEM
    HEBDEN, JC
    KRUGER, RA
    [J]. MEDICAL PHYSICS, 1990, 17 (03) : 351 - 356
  • [9] TRANSILLUMINATION IMAGING PERFORMANCE - SPATIAL-RESOLUTION SIMULATION STUDIES
    HEBDEN, JC
    KRUGER, RA
    [J]. MEDICAL PHYSICS, 1990, 17 (01) : 41 - 47
  • [10] HEBDEN JC, 1991, SPIE S TIM RES SPECT, V1431, P225