CLINICOPATHOLOGICAL STUDIES OF IMMUNOLOGICAL FECAL OCCULT BLOOD-TEST FOR COLORECTAL-CANCER

被引：11

作者：

IIDA, Y

MUNEMOTO, Y

MIURA, S

KASAHARA, Y

SAITO, H

MITSUI, T

ASADA, Y

FUKUOKA, K

TOYA, D

TANAKA, N

KIMURA, A

FUJISAWA, M

机构：

[1] Department of Surgery, Fukui-ken Saiseikai Hospital, Fukui, 910, 7-1 Funabashi, Wadanaka-cho

[2] Department of Internal Medicine, Fukui-ken Saiseikai Hospital, Fukui, 910, 7-1 Funabashi, Wadanaka-cho

[3] Department of Pathology, Fukui-ken Saiseikai Hospital, Fukui, 910, 7-1 Funabashi, Wadanaka-cho

来源：

JOURNAL OF GASTROENTEROLOGY | 1995年 / 30卷 / 02期

关键词：

FECAL OCCULT BLOOD TEST; COLORECTAL CANCER; IMMUNOLOGICAL FECAL OCCULT BLOOD TEST; LATEX AGGLUTINATION METHOD; FALSE NEGATIVE;

D O I：

10.1007/BF02348665

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

In our hospital, 83 patients with colorectal cancer underwent the immunologic fecal occult blood test (IFOBT). The positive rate for IFOBT in all patients was 87%. Colon cancers more proximal than the transverse colon were 100% positive. Carcinomas of the ulcerative type showed a significantly higher positive rate than those of the non-ulcerative type (94% vs 73%). Carcinomas penetrating the muscularis or beyond showed a significantly higher positive rate, of 96% (52/54 cases) compared to carcinomas confined to the mucosa or submucosa, which gave positive rates of 64% and 60%, respectively. In the investigation of the 7 patients with colorectal cancer who showed negative results on the IFOBT, IFOBT had been performed only once in of these patients. Accordingly, it was considered necessary to perform IFOBT more than once. The cancers in 5 of these 7 patients were found to be carcinomas confined to the mucosa. This result suggests the advisability of annual IFOBTs. It is also considered necessary to manage patients who show undefinable but possibly positive (+/-) results with caution.

引用

页码：195 / 200

页数：6

共 12 条

[1]

Vital Statistics 1985 Japan, 1, pp. 248-263, (1985)

[2]

Saito H., Tsuchida S., Fujita H., Et al., An immunological test for fecal occult blood by counter immunoelectrophoresis, Jpn Gastroenterol, 79, pp. 1944-1949, (1982)

[3]

Saito H., Tsuchida S., Fukushi M., Et al., An immunological test for fecal occult blood by counter immunoelectrophoresis: A following report, Jpn J Gastroenterol, 81, pp. 2935-2939, (1984)

[4]

Hagiwara H., Shimonaka M., Sakurai Y., Et al., Immunochemical detection of human denatured hemoglobin in occult blood, Clin Chim Acta, 136, pp. 245-249, (1984)

[5]

Saito H., Tsuchida S., Nakajima S., Et al., An immunologic test for fecal occult blood by counter immunoelectrophoresis, Cancer, 56, pp. 1549-1552, (1985)

[6]

Turnen M.J., Liewendahl K., Partanen P., Et al., Immunological detection of fecal occult blood in colorectal cancer, British Journal of Cancer, 49, pp. 141-148, (1984)

[7]

Songster C.L., Barrows G.H., Jarrett D.D., Immunochemical detection of fecal occult blood, Cancer, 45, pp. 1099-1102, (1980)

[8]

Saito H., Tsuchida S., Kakizaki R., Et al., An immunological fecal occult blood test for mass screening of colorectal cancer by reversed passive hemagglutination (RPHA), Jpn J Gastroenterol, 81, (1984)

[9]

Ada E.C., Layman K.M., Immunochemical confirmation of gastrointestinal bleeding, Ann Clin Lab Sci, 4, pp. 343-349, (1974)

[10]

Takeshita T., Horiguchi J., Kinoshita T., Et al., Latex agglutination test for fecal occult blood, J Jpn Soc Colo-Proctol, 38, pp. 780-783, (1985)

← 1 2 →