DIRECT BROMINATION OR HYDROXYLATION AT C-11 IN VINCADIFFORMINE AND TABERSONINE DERIVATIVES IN SUPERACIDS

被引：9

作者：

BERRIER, C ^{[1
]}

JACQUESY, JC ^{[1
]}

JOUANNETAUD, MP ^{[1
]}

VIDAL, Y ^{[1
]}

机构：

[1] FAC SCI POITIERS,CHIM LAB 12,CNRS,URA DO 489,40 AVE RECTEUR PINEAU,F-86022 POITIERS,FRANCE

来源：

TETRAHEDRON | 1990年 / 46卷 / 03期

关键词：

D O I：

10.1016/S0040-4020(01)81365-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In HF-SbF5, vincadifformine 1b reacts with H2O2 to yield a mixture (60%) of hydroxyderivatives 1c and 1d. 2,16-Dihydrovincadifformine 2a is more selectively hydroxylated at C-11 to give 2b (40%); in a similar reaction, 2d yields 2e (37%). Reaction of 2a with Br2 in HF-SbF5 gives regioselectively compound 2c (80%). © 1990.

引用

页码：827 / 832

页数：6

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