A SIMPLE METHOD FOR THE MICROSCALE PREPARATION OF MOSHER ACID CHLORIDE

被引：181

作者：

WARD, DE

RHEE, CK

机构：

[1] Department of Chemistry, University of Saskatchewan, Saskatoon

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 49期

关键词：

MOSHER ACID; MOSHER ACID CHLORIDE; MOSHER ESTERS; PREPARATION OF ACID CHLORIDES; MICROSCALE;

D O I：

10.1016/0040-4039(91)80466-J

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Mosher's acid is treated with oxalyl chloride in the presence of DMF in hexane. Filtration and concentration provide the acid chloride which is suitable for use without further purification. The procedure is amenable to microscale.

引用

页码：7165 / 7166

页数：2

共 13 条

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