VARIABILITY IN THE SUSCEPTIBILITY PATTERN OF BACTEROIDES-FRAGILIS IN 4 DETROIT AREA HOSPITALS

被引：39

作者：

BAWDON, RE ^{[1
]}

ROZMIEJ, E ^{[1
]}

PALCHAUDHURI, S ^{[1
]}

KRAKOWIAK, J ^{[1
]}

机构：

[1] WAYNE STATE UNIV, SCH MED, DEPT PATHOL, DETROIT, MI 48201 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1979年 / 16卷 / 05期

关键词：

D O I：

10.1128/AAC.16.5.664

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Recent clinical isolates of Bacteroides fragilis selected at random from four Detroit area hospitals were collected over a 3-month period, and the minimum inhibitory concentrations were determined within several days. The levels of antimicrobial agents used in this survey breached the concentration attainable in the patient's serum. The antimicrobial susceptibility patterns of these isolates to five antimicrobial agents suggest that there is a 20% variation in the resistance to clindamycin and also up to 20% variation among the other four antibiotics in the four area hospitals. The changing susceptibility pattern of B. fragilis to antibiotic resistance suggests that minimum inhibitory concentrations should be determined for all isolates from serious clinical infections.

引用

页码：664 / 666

页数：3

共 11 条

[1] ANTIBIOTIC SUSCEPTIBILITY OF SUBSPECIES OF BACTEROIDES-FRAGILIS [J].

BLAZEVIC, DJ .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1976, 9 (03) :481-484

[2]

DOWELL UR, 1974, LABORATORY METHODS A

[3]

FINEGOLD SM, 1977, ANAEROBIC BACTERIA H, pCH18

[4] IDENTIFICATION OF A CONJUGATIVE R-PLASMID IN BACTEROIDES-OCHRACEUS CAPABLE OF TRANSFER TO ESCHERICHIA-COLI [J].

GUINEY, DG ;

DAVIS, CE .

NATURE, 1978, 274 (5667) :181-182

[5]

HOLDEMAN LV, 1970, ANAEROBIC LABORATORY

[6]

Lennette E.H., 1974, MANUAL CLIN MICROBIO, P410

[7] BACTEROIDES FRAGILIS RESISTANT TO ADMINISTRATION OF CLINDAMYCIN [J].

SALAKI, JS ;

BLACK, R ;

TALLY, FP ;

KISLAK, JW .

AMERICAN JOURNAL OF MEDICINE, 1976, 60 (03) :426-428

[8] ANAEROBES AND TRANSFERABLE DRUG-RESISTANCE [J].

SAUNDERS, JR .

NATURE, 1978, 274 (5667) :113-114

[9] SUSCEPTIBILITY OF ANAEROBIC BACTERIA TO 23 ANTIMICROBIAL AGENTS [J].

SUTTER, VL ;

FINEGOLD, SM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1976, 10 (04) :736-752

[10] MEDIUM FOR USE IN ANTIBIOTIC SUSCEPTIBILITY TESTING OF ANAEROBIC BACTERIA [J].

WILKINS, TD ;

CHALGREN, S .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1976, 10 (06) :926-928

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