ENZYMATIC RESOLUTION OF 3-SUBSTITUTED-4-OXOESTERS

被引：14

作者：

BLANCO, L

ROUSSEAU, G

BARNIER, JP

GUIBEJAMPEL, E

机构：

[1] Laboratoire des Carbocycles, Associé au CNRS, Institut de Chimie Moléculaire d'Orsay, 91405 Orsay

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 05期

关键词：

D O I：

10.1016/S0957-4166(00)80116-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The lipase catalyzed hydrolysis of cyanomethyl 3-substituted-4-oxoesters was studied. With 3-methyl substituted esters, PPL led to optically active compounds. When the 3-substituent was a larger group, more satisfactory results were obtained with PL, especially if the substituent attached to the ketone function is other from methyl.

引用

页码：783 / 792

页数：10

共 31 条

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