WEIGHT CHANGES WITH DEPOT NEUROLEPTIC MAINTENANCE THERAPY

被引：34

作者：

JOHNSON, DAW

BREEN, M

机构：

[1] Department of Psychiatry, University Hospital of South Manchester, Manchester, West Didsbury

来源：

ACTA PSYCHIATRICA SCANDINAVICA | 1979年 / 59卷 / 05期

关键词：

anti‐parkinsonian drugs; continues; 2; years; dose; Flupenthixol decanoate; fluphenazine decanoate ‐maintenance therapy; significant weight gain; unrelated; weight change;

D O I：

10.1111/j.1600-0447.1979.tb00252.x

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

A prospective study of schizophrenic patients prescribed injectable depot neuroleptic drugs as maintenance therapy showed a clinically significant weight gain in 55 % of patients. No significant difference was shown between flupenthixol decanoate and fluphenazine decanoate, nor was a clinically meaningful relationship shown with dose, or the use of anti‐parkinsonian drugs. The weight gain continued for at least 2 years following a mental state relapse. It is suggested that the monitoring of weight and giving of appropriate advice on diet are two essentials in maintenance therapy of chronic schizophrenia. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：525 / 528

页数：4

共 8 条

[1]

AMDISEN A, 1964, Dan Med Bull, V11, P182

[2]

AYD FJ, 1975, AM J PSYCHIAT, V132, P491

[3] DOUBLE-BLIND CONTROLLED-STUDY OF PIPOTHIAZINE PALMITATE IN MAINTENANCE TREATMENT OF SCHIZOPHRENIC OUTPATIENTS [J].