WEIGHT CHANGES WITH DEPOT NEUROLEPTIC MAINTENANCE THERAPY

被引:34
作者
JOHNSON, DAW
BREEN, M
机构
[1] Department of Psychiatry, University Hospital of South Manchester, Manchester, West Didsbury
关键词
anti‐parkinsonian drugs; continues; 2; years; dose; Flupenthixol decanoate; fluphenazine decanoate ‐maintenance therapy; significant weight gain; unrelated; weight change;
D O I
10.1111/j.1600-0447.1979.tb00252.x
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
A prospective study of schizophrenic patients prescribed injectable depot neuroleptic drugs as maintenance therapy showed a clinically significant weight gain in 55 % of patients. No significant difference was shown between flupenthixol decanoate and fluphenazine decanoate, nor was a clinically meaningful relationship shown with dose, or the use of anti‐parkinsonian drugs. The weight gain continued for at least 2 years following a mental state relapse. It is suggested that the monitoring of weight and giving of appropriate advice on diet are two essentials in maintenance therapy of chronic schizophrenia. Copyright © 1979, Wiley Blackwell. All rights reserved
引用
收藏
页码:525 / 528
页数:4
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