BEHAVIORAL TREATMENT OF OBSESSIONAL-COMPULSIVE DISORDERS, WITH AND WITHOUT CLOMIPRAMINE

The effects of behavioural treatment alone, and in combination with clomipramine, were assessed on 40 patients with chronic obsessional-compulsive disorders, using a 2 × 2 factorial design. These effects were assessed by behavioural measures and mood measures. The behavioural treatment was followed by significant improvements on most behavioural measures. Clomipramine administration was followed by significant improvements on mood scales and some behavioural measures. There were no significant interactions between these two experimental conditions. © 1979.